Author

Smita Kulkarni

Texas Biomedical Research InstituteORCID 0000-0002-3777-5972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hoang NguyeniD· 2 shared Sahana JayakumariD· 2 shared Ajai Lawrence D’silvaiD· 1 shared Anu Gopal· 1 shared Asha Thomas· 1 shared Hannah Wilson· 1 shared Marija A. DjurkoviciD· 1 shared Olena ShtankoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Hoang NguyenORCID

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2 papers

Recent·Most cited

Ebola virus exploits host lncRNA LINC01740 to enhance ATF3 and suppress antiviral immune responses

Olena Shtanko, Tanuj Gunturu, Anu Gopal, Marija A. Djurkovic, Hoang Nguyen, Sahana Jayakumar, Ajai Lawrence D’silva, Asha Thomas, Smita Kulkarni

This study identifies LINC01740 as a host lncRNA that EBOV uses to enhance ATF3 and suppress antiviral immune responses in macrophages.

bioRxiv · Jul 9, 2026 · PreprintImmunology

Efficient inhibition of HIV using CRISPR/Cas13d nuclease system

Hoang Nguyen, Hannah Wilson, Sahana Jayakumar, Viraj Kulkarni, Smita Kulkarni

This study shows CRISPR/Cas13d can inhibit HIV-1 replication in cell lines and primary T-cells, including latent infections, by targeting multiple sites in the HIV-1 transcript.

Viruses · Sep 16, 2021Peer-reviewedMolecular Biology