Viraj Kulkarni

This study shows Maftivimab neutralizes BDBV-2026 and protects non-human primates from BDBV disease when administered after infection.

A single dose of alum-adjuvanted RBD protein vaccine from the Wuhan strain protects against homologous SARS-CoV-2 WA strain challenge but not heterologous Delta and Omicron BA.5 rechallenge, unless mice survive the initial WA challenge.

6-Thioguanine inhibits SARS-CoV-2 PLpro protease activity and replication in cell cultures at submicromolar concentrations.

This study shows CRISPR/Cas13d can inhibit HIV-1 replication in cell lines and primary T-cells, including latent infections, by targeting multiple sites in the HIV-1 transcript.