Nicholas A. Nelson

The paper develops a computational model of astrocytic calcium signaling that predicts refractory periods through a feedback mechanism involving cPKC, validated with in vivo imaging data.

This paper develops a new imaging system to study spinal cord activity in behaving mice, revealing lamina-specific calcium responses in astrocytes and pain-related activity in Tac1 neurons.

This study develops a wearable macroscope to image spinal cord activity in behaving mice and finds that painful stimuli trigger coordinated astrocyte excitation across multiple spinal segments.