BiochemistryRedox BiologyPeer-reviewed
The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2.
Jialin Feng, Mara Carreño, Hannah Jung…·Albena T. Dinkova‐Kostova
This study shows that kynurenine-CKA targets C151 in Keap1 to increase Nrf2 activity and anti-inflammatory effects in macrophages.
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