Author

Dorothy Kisielewski

The University of QueenslandORCID 0000-0001-9402-3913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Abel Damien AngiD· 1 shared Aimee L. EggleriD· 1 shared Alan Richard ClarkeiD· 1 shared Albena T. Dinkova‐KostovaiD· 1 shared Alison Marshall· 1 shared Barry Matthew BradfordiD· 1 shared Beatriz LeóniD· 1 shared Bhargavi Kulkarni· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abel Damien AngORCID

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2 papers

Recent·Most cited

BiochemistryRedox BiologyPeer-reviewedJan 6, 2026

The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2.

Jialin Feng, Mara Carreño, Hannah Jung…·Albena T. Dinkova‐Kostova

This study shows that kynurenine-CKA targets C151 in Keap1 to increase Nrf2 activity and anti-inflammatory effects in macrophages.

4 citationstop 3%

mouseproteomics

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NeurosciencebioRxivPreprintNov 18, 2024

Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein

Barry Matthew Bradford, Alison Marshall, Nadia L. Tuzi…·Jean C. Manson

This study defines a therapeutic window for prion disease by showing early Prnp depletion halts progression, but later depletion does not, using a mouse model with time-dependent Prnp manipulation.

DOI 10.1101/2024.11.18.624122

mouseexperimental assay

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