Author

Jan Zethof

Radboud University NijmegenORCID 0000-0002-3793-6318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Juriaan Rogier MetziD· 2 shared Ankit ShuklaiD· 1 shared Annemieke Kleinhout-van Vuuren· 1 shared Camiel J. F. BooniD· 1 shared Charles R. HelleriD· 1 shared Chrissy L. HammondiD· 1 shared Daniël L. A. H. HornikxiD· 1 shared Drew N. RobsoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

Juriaan Rogier MetzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Usherin in the pineal gland: altered sleep in zebrafish models of Usher syndrome type 2a

Jessie M. Hendricks, Vikash Choudhary, Charles R. Heller, Mel van Gemert, Daniël L. A. H. Hornikx, Sanne Broekman, Theo A. Peters, Jan Zethof, Jonathan Hensman, Camiel J. F. Boon, Drew N. Robson, Jennifer Li, Rianne Ligterink, Annemieke Kleinhout-van Vuuren, Silvia C. Endenburg, , Erwin van Wijk

This study investigates the role of usherin in zebrafish sleep regulation, finding altered sleep-wake behavior in ush2a mutants despite normal circadian rhythms and melatonin release.

bioRxiv · Mar 11, 2026 · PreprintAnimal Behavior & Cognition

foxe1 mutant zebrafish show indications of a hypothyroid phenotype and increased sensitivity to ethanol for craniofacial malformations

Sophie T. Raterman, Frank A. D. T. G. Wagener, Jan Zethof, Vincent M.J.I. Cuijpers, Peter H.M. Klaren, Juriaan Rogier Metz, Johannes W. Von den Hoff

This study shows foxe1 mutant zebrafish exhibit hypothyroidism and increased ethanol-induced craniofacial malformations, mirroring human FOXE1 mutation phenotypes.

Developmental Dynamics · Oct 3, 2024Peer-reviewedDevelopmental Biology

The transcriptome of regenerating zebrafish scales identifies genes involved in human bone disease

Dylan J. M. Bergen, Qiao Tong, Ankit Shukla, Elis Newman, Jan Zethof, Mischa Lundberg, Rebecca Ryan, Scott E. Youlten, Eleftheria Zeggini, Peter Ian Croucher, Gert Flik, Rebecca J. Richardson, John P. Kemp, Chrissy L. Hammond, Juriaan R. Metz

The paper identifies genes involved in human bone disease by analyzing transcriptomic changes during zebrafish scale regeneration.

BMC Biology · Jan 20, 2022Peer-reviewedGenetics