A systems genomics approach uncovers molecular associates of RSV severity
Matthew N. McCall, Chin‐Yi Chu, Lu Wang…·Thomas J. Mariani
The paper integrates multi-omic data to identify cellular pathways associated with RSV severity in infants.
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University of Rochester MedicineORCID 0000-0002-3813-0762Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Matthew N. McCall, Chin‐Yi Chu, Lu Wang…·Thomas J. Mariani
The paper integrates multi-omic data to identify cellular pathways associated with RSV severity in infants.
Chin‐Yi Chu, Xing Qiu, Matthew N. McCall…·Thomas J. Mariani
The paper identifies a lack of airway interferon activation as a marker of severe infant RSV infection and shows that blocking IFN signaling increases viral infection in vitro.
Alex Grier, Andrew McDavid, Bokai Wang…·Steven R. Gill
The paper examines co-occurrence patterns of gut and respiratory microbiota in pre- and full-term infants over the first year, identifying three patterns of CST manifestation related to infant maturity.