Chin‐Yi Chu

This study uses single-cell RNA sequencing to analyze age and cell population-specific responses to SARS-CoV-2 infection in lung epithelial cells, identifying differences in innate immune signaling between pediatric and adult tissues.

The paper integrates multi-omic data to identify cellular pathways associated with RSV severity in infants.

The paper identifies a lack of airway interferon activation as a marker of severe infant RSV infection and shows that blocking IFN signaling increases viral infection in vitro.