Author

John C. Dittmar

Columbia UniversityORCID 0000-0002-3820-1612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

Aidin Shabro· 1 shared David OntosoiD· 1 shared John L. NitissiD· 1 shared Monika MehtaiD· 1 shared Robert J. D. ReidiD· 1 shared Rodney J. RothsteiniD· 1 shared Scott KeeneyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Aidin Shabro

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1 paper

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedSep 1, 2026

A multi-species toolkit of TOP2 hypercleavage mutants for studying topoisomerase II-mediated DNA damage

David Ontoso, Monika Mehta, Aidin Shabro…·Scott Keeney

The paper develops hypercleavage TOP2 mutants in yeast, human, and mouse to study TOP2-mediated DNA damage and toxicity, showing their utility in genetic screens and in vivo models.

DOI 10.1073/pnas.2616452123

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