Brain tumor induce immunoregulatory dendritic cells in tumor draining lymph nodes that can be targeted by OX40
O. Badillo, Jenni Viivi Linnea Niemi, Liam Helfridsson, Shokoufeh Karimi, Mohanraj Ramachandran, Hitesh Bhagavanbhai Mangukiya, Sven Nelander, Mats Hellström
This study identifies immunoregulatory dendritic cells in brain tumor draining lymph nodes and shows OX40 can target them to improve immunotherapy.
Journal for ImmunoTherapy of Cancer · May 1, 2025Peer-reviewedImmunology