Author

Reinhard Roessler

Whitehead Institute for Biomedical ResearchORCID 0000-0002-3841-3404Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Chikdu Shivalila· 1 shared Johanna E. Goldmann· 1 shared Rudolf JaenischiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperNeuroscience

Chikdu Shivalila

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1 paper

Recent·Most cited

JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell-derived neural progenitors and cortical neurons.

Reinhard Roessler, Johanna E. Goldmann, Chikdu Shivalila, Rudolf Jaenisch

The paper investigates the role of JIP2 haploinsufficiency in neurodevelopmental abnormalities using human pluripotent stem cells and finds that it impairs neuronal maturation through JNK misregulation and compromised semaphorin signaling.

Life Science Alliance · Jun 25, 2018Peer-reviewedNeuroscience