Author

Johanna E. Goldmann

Whitehead Institute for Biomedical Research

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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Chikdu Shivalila· 1 shared Reinhard RoessleriD· 1 shared Rudolf JaenischiD· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperNeuroscience

Chikdu Shivalila

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1 paper

Recent·Most cited

NeuroscienceLife Science AlliancePeer-reviewedJun 25, 2018

JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell-derived neural progenitors and cortical neurons.

Reinhard Roessler, Johanna E. Goldmann, Chikdu Shivalila, Rudolf Jaenisch

The paper investigates the role of JIP2 haploinsufficiency in neurodevelopmental abnormalities using human pluripotent stem cells and finds that it impairs neuronal maturation through JNK misregulation and compromised semaphorin signaling.

10 citations

humanbulk RNA-seq

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