Author

Trevor F. Freeman

University of Tennessee at KnoxvilleORCID 0000-0002-3888-8987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:Hi-C· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Rachel Patton McCordiD· 2 shared Rosela GolloshiiD· 2 shared Adayabalam S. BalajeeiD· 1 shared Ashtyn M HilliD· 1 shared Christopher PlayteriD· 1 shared Delaney Thurston· 1 shared Jacob T. SandersiD· 1 shared Joshua H. Garretson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Rachel Patton McCordORCID

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2 papers

Recent·Most cited

Systems BiologyEMBO ReportsPeer-reviewedAug 15, 2022

Constricted migration is associated with stable 3D genome structure differences in cancer cells

Rosela Golloshi, Christopher Playter, Trevor F. Freeman…·Rachel Patton McCord

This study shows that constricted migration in cancer cells leads to stable 3D genome structure changes associated with increased migration efficiency and altered gene expression.

53 citations

humanHi-C

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GenomicsNature CommunicationsPeer-reviewedDec 2, 2020

Radiation-Induced DNA Damage and Repair Effects on 3D Genome Organization

Jacob T. Sanders, Trevor F. Freeman, Yang Xu…·Rachel Patton McCord

This study examines how DNA damage and repair affect 3D genome organization using Hi-C in different cell types, finding cell-type-specific changes and TAD boundary strengthening in repair-proficient cells.

134 citationstop 2%

humanHi-C

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