Author

William P. Tansey

Vanderbilt UniversityORCID 0000-0002-3900-0978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brian C. GriebiD· 2 shared Alan J. SimmonsiD· 1 shared Alexis B. RobersoniD· 1 shared Bavavarshini Tamilselvam· 1 shared Christian R. de CaesteckeriD· 1 shared Emilie L. FisheriD· 1 shared Ian G. MacaraiD· 1 shared James MarksiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Brian C. GriebORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 31, 2026

5-Azacytidine incorporation into mRNAs disrupts translation and induces ribosome collisions

Alexis B. Roberson, James Marks, Ruby Pitts…·Sezen Meydan

This study shows 5-AzaC incorporation into mRNAs disrupts translation, causes ribosome collisions, and activates stress responses, contributing to its cytotoxicity beyond DNA hypomethylation.

1 citation

humanRibo-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 1, 2024

Scalable single-cell pooled CRISPR screens with conventional knockout vector libraries

Mirazul Islam, Yilin Yang, Alan J. Simmons…·Ken S. Lau

This paper introduces NSC-seq, a direct sgRNA capture method for single-cell CRISPR screens using standard knockout libraries, and characterizes sgRNA expression in three whole-genome libraries.

1 citation

CRISPR screenexperimental assay

𝕏 PostBluesky