A small molecule enhances arrestin-3 binding to the β2-adrenergic receptor
Han Kurt, Ali Akyol, Çağdaş Devrim Son, Chen Zheng, Irene Gado, Massimiliano Meli, Erica Elisa Ferrandi, Ivan Bassanini, Francesca Vasile, Vsevolod V. Gurevich, Aylin Nebol, Esra Çağavi, Giulia Morra, Özge Şensoy
A small molecule stabilizes the pre-activated state of arrestin-3, enhancing its binding to phosphorylation-deficient β2-adrenergic receptors.
Communications Chemistry · Jul 1, 2025Peer-reviewedCell Biology