Massimiliano Meli

This paper introduces a deep learning method to identify conformational binding signatures in protein dynamics from molecular simulations.

This study uses cryo-EM to reveal how microtubule association induces an Mg-free apo-like ADP pre-release conformation in kinesin-1, independent of tail interactions.

A small molecule stabilizes the pre-activated state of arrestin-3, enhancing its binding to phosphorylation-deficient β2-adrenergic receptors.

This study investigates clinically relevant cytochrome c variants using bioinformatics and molecular dynamics to reveal structural and functional changes linked to thrombocytopenia 4.