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The paper identifies conserved actin-driven mechanisms in jellyfish oocytes that facilitate meiosis, suggesting ancient origins in metazoans.

AutoSTED automates the identification and super-resolution imaging of cell nuclei, enabling unbiased large-scale data collection.

The paper shows oocyte nuclei mimic cellular shape under deformation due to soft nucleoplasm and viscoelastic cytoplasm, with cytoplasmic elasticity affecting nuclear deformation across species.

This study shows that Plk1 inhibition delays mitotic entry, revealing prophase-specific phosphoproteome changes and highlighting Plk1's role in the prophase to prometaphase transition.