Age-Dependent Increase and Dysregulation of the Splicing Machinery in Acute Myeloid Leukemia of Older Patients
Jordan B. Burton, Kristin M. Pladna, Joanna Bons, Mark A. Watson, Christina D. King, Timothy S. Pardee, Birgit Schilling
This study identifies age-related dysregulation of the splicing machinery in older AML patients through proteomic analysis, highlighting potential targets for age-specific therapies.
bioRxiv · Jul 4, 2025 · PreprintCancer Biology