Jean‐Philippe David

Novel ddPCR diagnostic assays for the high-throughput surveillance of Kdr mutations in Aedes albopictus

The paper develops ddPCR assays for high-throughput Kdr mutation surveillance in Aedes albopictus, showing high accuracy and low mutation prevalence in French populations.

Metabolic resistance of the tiger mosquito to pyrethroid insecticides in La Reunion Island likely results from local adaptation

This study identifies genetic mechanisms of pyrethroid resistance in La Reunion Island tiger mosquitoes, showing it results from local adaptation through detoxification gene over-expression and a large inverted superlocus.

A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti

This study identifies a genomic duplication of multiple P450 genes in Aedes aegypti that enhances deltamethrin resistance and reveals its evolutionary origin and fitness costs.

Combining genetic crosses and pool targeted DNA-seq for untangling genomic variations associated with resistance to multiple insecticides in the dengue vector Aedes aegypti

This study combines genetic crosses with targeted DNA sequencing to identify resistance alleles in multi-resistant Aedes aegypti mosquitoes exposed to insecticides.