Author

Robert B. Heuschkel

Addenbrooke's HospitalORCID 0000-0002-3992-1347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

April Rose FosteriD· 1 shared Aurélie CenieriD· 1 shared Camilla Salvestrini· 1 shared D. Leanne JonesiD· 1 shared Daniel R. ZerbinoiD· 1 shared Felicity PayneiD· 1 shared Francesca Marta Perrone· 1 shared Franco TorrenteiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

April Rose FosterORCID

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1 paper

Recent·Most cited

GenomicsCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2022

Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids

Rachel D. Edgar, Francesca Marta Perrone, April Rose Foster…·Matthias Zilbauer

This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.

40 citations

humanDNA methylation

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