Author

D. Leanne Jones

University of California, Los AngelesORCID 0000-0001-5721-6310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexa C. KwangiD· 1 shared April Rose FosteriD· 1 shared Aurélie CenieriD· 1 shared Camilla Salvestrini· 1 shared Cecilia D’Alterio· 1 shared Daniel R. ZerbinoiD· 1 shared Felicity PayneiD· 1 shared Francesca Marta Perrone· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Alexa C. KwangORCID

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2 papers

Recent·Most cited

Developmental BiologyPLoS ONEPeer-reviewedMar 21, 2024

mTORC1 is required for differentiation of germline stem cells in the Drosophila melanogaster testis

Marie Clémot, Cecilia D’Alterio, Alexa C. Kwang, D. Leanne Jones

This study shows that mTORC1 is essential for differentiation of germline stem cells in Drosophila melanogaster testis, with Tor downregulation causing differentiation block and somatic cell activation.

8 citations

Drosophilaexperimental assay

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GenomicsCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2022

Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids

Rachel D. Edgar, Francesca Marta Perrone, April Rose Foster…·Matthias Zilbauer

This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.

40 citations

humanDNA methylation

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