Author

Sharon Abrahams

Euan MacDonald Centre for Motor Neuron Disease ResearchORCID 0000-0002-3996-4574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Christopher R. SibleyiD· 2 shared Jenna M. GregoryiD· 2 shared Judi O’ShaughnessyiD· 2 shared Michael D.E. SewelliD· 2 shared Olivia M. RifaiiD· 2 shared Alison F. MunroiD· 1 shared Barry W. McColliD· 1 shared Fergal M. WaldroniD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Christopher R. SibleyORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 19, 2023

Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts

Olivia M. Rifai, Judi O’Shaughnessy, Owen Dando…·Jenna M. Gregory

The paper identifies two distinct neuroinflammatory signatures in ALS cohorts using gene expression analysis and validates their association with clinical metrics.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceThe Journal of PathologyPeer-reviewedSep 7, 2022

Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis

Olivia M. Rifai, James Longden, Judi O’Shaughnessy…·Jenna M. Gregory

The paper uses random forest modelling to identify microglial activation as a key classifier for C9orf72-related ALS and shows spatial FUS staining changes predict disease status.

21 citations

humanspatial transcriptomics

𝕏 PostBluesky