A live tumor fragment platform to assess immunotherapy response in core needle biopsies while addressing challenges of tumor heterogeneity
T. S. Ramasubramanian, Pichet Adstamongkonkul, Christina M. Scribano, Christin Johnson, Sean R. Caenepeel, Laura Hrycyniak, Lindsey Vedder, Nicholas Dana, Christian Baltes, Victoria L. Browning, Yuan‐I Chen, Thomas Dietz, Evan Flietner, Nicholas Kaplewski, Anna V. Kellner, , Hinco Jasper Gierman
This paper introduces a live tumor fragment platform to assess immunotherapy response in core needle biopsies, showing it can detect T-cell responses and mitigate tissue heterogeneity challenges.
Journal of Translational Medicine · Jan 3, 2026Peer-reviewedCancer Biology