Author

João Marcelo Lamim Ribeiro

Icahn School of Medicine at Mount SinaiORCID 0000-0002-4004-285XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

João Marcelo Lamim Ribeiro1 paper

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1

Frequent Co-Authors

Davide ProvasiiD· 2 shared Leslie A. Salas-EstradaiD· 2 shared Marta FilizolaiD· 2 shared Alexa StraussiD· 1 shared Bryan L. RothiD· 1 shared Guoqing XiangiD· 1 shared H. Ümit KanıskaniD· 1 shared Jean‐Yves Tano· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Davide ProvasiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep Learning Framework

Leslie A. Salas-Estrada, Davide Provasi, Xing Qiu, H. Ümit Kanıskan, Xi‐Ping Huang, Jeffrey F. DiBerto, João Marcelo Lamim Ribeiro, Jian Jun Jin, Bryan L. Roth, Marta Filizola

This study uses a generative deep learning framework to design new KOR antagonists, which are prioritized for synthesis and validated through experimental assays.

Journal of Chemical Information and Modeling · Aug 9, 2023Peer-reviewedBioinformatics

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors

Jordana K. Thibado, Jean‐Yves Tano, Joon Lee, Leslie A. Salas-Estrada, Davide Provasi, Alexa Strauss, João Marcelo Lamim Ribeiro, Guoqing Xiang, Johannes Broichhagen, Marta Filizola, Martin J. Lohse, Joshua Levitz

This study identifies subtype-specific differences in transmembrane domain interactions that influence metabotropic glutamate receptor activation.

eLife · Apr 21, 2021Peer-reviewedNeuroscience