Francesca Spyrakis

This paper designs novel acyl carrier protein variants using a computational method, showing they can undergo post-translational modification despite lacking the canonical helical structure.

This study identifies calcium as a key regulator of Annexin-A11's function in RNA transport and its disruption in ALS by revealing its conformational switch and domain interactions.

This paper identifies C35 as a dual-acting compound that inhibits Staphylococcus aureus growth by blocking heme acquisition and modulates hemoglobin oxygen affinity.