Author

Marialaura Marchetti

University of ParmaORCID 0000-0002-4615-6786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Barbara CampaniniiD· 2 shared Emanuela FrangipaniiD· 2 shared Luca RondaiD· 2 shared Omar De BeiiD· 2 shared Sarah HijaziiD· 2 shared Serena FaggianoiD· 2 shared Stefano BettatiiD· 2 shared Valeria Buoli ComaniiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

Barbara CampaniniORCID

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2 papers

Recent·Most cited

IsdH binding to hemoglobin:haptoglobin is decoupled from iron acquisition in Staphylococcus aureus

Valeria Buoli Comani, Omar De Bei, Sarah Hijazi, Antonio Cataldi, Giulia Paris, Giulia Sassi, Marialaura Marchetti, Barbara Campanini, Luca Ronda, Serena Faggiano, Ben F. Luisi, Emanuela Frangipani, Stefano Bettati

This study shows IsdH binds HbHp but does not support S. aureus growth under iron restriction when HbHp is the sole iron source, suggesting HbHp recognition has roles beyond iron acquisition.

bioRxiv · Jun 18, 2026 · PreprintBiochemistry

Two birds with one stone: a novel potential antibiotic blocking IsdB-mediated heme extraction by Staphylococcus aureus with serendipitous hemoglobin left-shifting activity

Sarah Hijazi, Francesco Marchesani, Marialaura Marchetti, Valeria Buoli Comani, P. Brear, Barbara Campanini, Luca Ronda, Serena Faggiano, Eleonora Gianquinto, Somayeh Asghar Pour Hassan Kiyadeh, Barbara Rolando, Francesca Spyrakis, Carlotta Compari, Loretta Lazzarato, Omar De Bei, , Stefano Bettati

This paper identifies C35 as a dual-acting compound that inhibits Staphylococcus aureus growth by blocking heme acquisition and modulates hemoglobin oxygen affinity.

bioRxiv · May 29, 2025 · PreprintMicrobiology