Host species background, defence systems, and phage tail gene architecture shape phage infectivity in cystic fibrosis-associated Achromobacter
A.B. Tarasenko, Bhavya Nalagampalli Papudeshi, Van Nguyen, Susanna R. Grigson, George Spyro Bouras, Vijini Mallawaarachchi, Abbey L. K. Hutton, Renee Green, Jack Ramsay, Hamza Hajama, Ana Georgina Cobián Güemes, Anca Mara Segall, Morgyn S. Warner, Sarah K. Giles, Clarice M. Harker, Robert Alan Edwards
The paper shows bacterial strain identity is the main factor determining phage infectivity in Achromobacter, with lineage and strain identity explaining 90% of variation in infection efficiency.
bioRxiv · Jul 1, 2026 · PreprintMolecular Biology