Author

Ian A. Nicastro

University of California San DiegoORCID 0000-0002-4058-4720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Amy E. PasquinelliiD· 2 shared Delaney C. DanniD· 1 shared Devavrat M. BodasiD· 1 shared Erin C SchiksnisiD· 1 shared Jesse J. HulahaniD· 1 shared Laura B. ChipmaniD· 1 shared San LuciD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Amy E. PasquinelliORCID

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2 papers

Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedNov 18, 2024

Full-length direct RNA sequencing reveals extensive remodeling of RNA expression, processing and modification in aging Caenorhabditis elegans

Erin C Schiksnis, Ian A. Nicastro, Amy E. Pasquinelli

This study uses full-length RNA sequencing to identify age-related changes in RNA expression, processing, and modification in C. elegans.

8 citations

C. eleganslong-read sequencing

GeneticsbioRxivPreprintMay 18, 2023

Expression, not sequence, distinguishes miR-238 from its miR-239ab sister miRNAs in promoting longevity in Caenorhabditis elegans

Laura B. Chipman, San Luc, Ian A. Nicastro…·Amy E. Pasquinelli

The paper shows that miR-238, not its sequence-similar miR-239ab siblings, promotes longevity in C. elegans through expression levels, not sequence differences.

DOI 10.1101/2023.05.18.541360

C. elegansexperimental assay