Author

Laura B. Chipman

Pfizer (United States)ORCID 0000-0002-5606-6143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Allison P. BergiD· 1 shared Amy E. PasquinelliiD· 1 shared Delaney C. DanniD· 1 shared Devavrat M. BodasiD· 1 shared Ian A. NicastroiD· 1 shared Jesse J. HulahaniD· 1 shared Kristin E. CoxiD· 1 shared Leah S. VandenBoschiD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperNeuroscience

Allison P. BergORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 28, 2023

Potentiating NaV1.1 in Dravet syndrome patient iPSC-derived GABAergic neurons increases neuronal firing frequency and decreases network synchrony

Matt R. Kelley, Laura B. Chipman, Shoh M. Asano…·Allison P. Berg

This study shows that enhancing NaV1.1 in Dravet syndrome patient neurons increases firing rates and reduces network synchrony using HD-MEAs.

DOI 10.1101/2023.09.28.559990

humanelectronic health records

𝕏 PostBluesky

GeneticsbioRxivPreprintMay 18, 2023

Expression, not sequence, distinguishes miR-238 from its miR-239ab sister miRNAs in promoting longevity in Caenorhabditis elegans

Laura B. Chipman, San Luc, Ian A. Nicastro…·Amy E. Pasquinelli

The paper shows that miR-238, not its sequence-similar miR-239ab siblings, promotes longevity in C. elegans through expression levels, not sequence differences.

DOI 10.1101/2023.05.18.541360

C. elegansexperimental assay

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Developmental BiologybioRxivPreprintSep 3, 2019

Cis-Regulatory Accessibility Directs Muller Glial Development and Regenerative Capacity

Leah S. VandenBosch, Stefanie G. Wohl, Matthew S. Wilken…·Thomas A. Reh

The paper identifies loss of neurogenic gene expression and motif accessibility in mature Muller glia that limits their regenerative capacity.

DOI 10.1101/752428

𝕏 PostBluesky