Integrated Molecular-Phenotypic Profiling Reveals Metabolic Control of Morphological Variation in Stembryos
Alba Villaronga Luque, Ryan G. Savill, Natalia López-Anguita, Adriano Bolondi, Sumit Garai, Seher Ipek Gassaloglu, Roua Rouatbi, Kathrin Schmeißer, Aayush Poddar, Lisa Bauer, Tiago C. Alves, Sofia Traikov, Jonathan Rodenfels, Triantafyllos Chavakis, Aydan Bulut-Karslıoğlu, Jesse V. Veenvliet
The paper identifies early metabolic imbalances as drivers of phenotypic variation in stembryos and shows how metabolic interventions can correct aberrant morphology and lineage bias.
Cell stem cell · Apr 16, 2025Peer-reviewedDevelopmental Biology