Alba Villaronga Luque

SpinePy enables automated 3D spatiotemporal quantification of multicellular in vitro systems

SpinePy provides a framework for 3D spatiotemporal quantification of multicellular systems by aligning data to dynamic internal coordinate systems, revealing patterning classes influenced by gastruloid volume.

Integrated Molecular-Phenotypic Profiling Reveals Metabolic Control of Morphological Variation in Stembryos

The paper identifies early metabolic imbalances as drivers of phenotypic variation in stembryos and shows how metabolic interventions can correct aberrant morphology and lineage bias.

Genome-wide identification of notochord enhancers comprising the regulatory landscape of the Brachyury (T) locus in mouse

The paper identifies thousands of notochord enhancers, including TNE2, using ATAC-seq and in vitro models, showing their role in T expression and tail development in mouse embryos.