Author

Jenny A Hurcombe

University of BristolORCID 0000-0002-4064-7306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron R. JeffriesiD· 1 shared Fern BarringtoniD· 1 shared Frédéric BurdetiD· 1 shared Gavin Iain WelshiD· 1 shared Joseph Talih CowardiD· 1 shared Lan NiiD· 1 shared Lusyan DayalaniD· 1 shared Mark IbbersoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aaron R. JeffriesORCID

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1 paper

Recent·Most cited

The insulin / IGF axis is critically important for controlling gene transcription in the podocyte.

Jenny A Hurcombe, Lusyan Dayalan, Fern Barrington, Frédéric Burdet, Lan Ni, Joseph Talih Coward, Mark Ibberson, Paul Thomas Brinkkoetter, Martin Holzenberger, Aaron R. Jeffries, Sebastian Oltean, Gavin Iain Welsh, Richard J. Coward

This study shows that insulin/IGF1 signaling in podocytes regulates gene transcription by affecting spliceosome function and protein modifications.

eLife · Sep 4, 2026Peer-reviewedCell Biology