Author

Paul T. Brinkkötter

InsermORCID 0000-0002-4287-2080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aaron R. JeffriesiD· 1 shared Andreas BeyeriD· 1 shared Bernhard SchermeriD· 1 shared Cem ÖzeliD· 1 shared Christian Vossen· 1 shared Christoph KuppeiD· 1 shared David Unnersjö‐JessiD· 1 shared F. Thomas WunderlichiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Aaron R. JeffriesORCID

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2 papers

Recent·Most cited

Cell BiologyeLifePeer-reviewedSep 4, 2026

The insulin / IGF axis is critically important for controlling gene transcription in the podocyte.

Jenny A Hurcombe, Lusyan Dayalan, Fern Barrington…·Richard J. Coward

This study shows that insulin/IGF1 signaling in podocytes regulates gene transcription by affecting spliceosome function and protein modifications.

DOI 10.7554/elife.107791.5

mouseproteomics

BioinformaticsbioRxivPreprintFeb 20, 2025

Single-Cell Resolution of Cellular Damage Illuminates Disease Progression

Tsimafei Padvitski, Paula Unger Avila, He Chen…·Andreas Beyer

The paper develops single-cell damage scores to quantify cellular deterioration in degenerative diseases and applies them to murine and human datasets to identify molecular trajectories of damage.

1 citation