Author

Giovanna Grandinetti

The Ohio State UniversityORCID 0000-0002-4073-0337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

James R. SellersiD· 1 shared Krishna ChinthalapudiiD· 1 shared Sarah M. HeissleriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

James R. SellersORCID

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1 paper

Recent·Most cited

Structural basis of nonmuscle myosin-2 autoinhibition mechanisms

Sarah M. Heissler, Giovanna Grandinetti, James R. Sellers, Krishna Chinthalapudi

The paper presents the cryo-EM structure of human NM2B in the autoinhibited 10S conformation, revealing structural mechanisms of autoinhibition and implications for disease.

Nature Communications · Jun 20, 2026Peer-reviewedBiophysics