Author

Giovanni Bussotti

InsermORCID 0000-0002-4078-7413Unclaimed ORCID profile · follow to get notified of new preprints

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Giovanni Bussotti1 paper

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Gerald Frank SpäthiD· 3 shared Anne BolandiD· 1 shared Disha‐Gajanan HiregangeiD· 1 shared Hasnaa TalimiiD· 1 shared Idris MhaidiiD· 1 shared Jean‐François DeleuzeiD· 1 shared K. Shanmugha RajaniD· 1 shared Laura PieliD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Gerald Frank SpäthORCID

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3 papers

Recent·Most cited

GenomicsMicrobial GenomicsPeer-reviewedApr 5, 2024

A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco

Hasnaa Talimi, Othmane Daoui, Giovanni Bussotti…·Gerald Frank Späth

The paper sequenced 14 Moroccan Leishmania tropica isolates to study genomic heterogeneity, identifying a core group and two divergent strains with distinct SNP profiles.

9 citations

whole-genome sequencingstatistical model

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GenomicsProceedings of the National Academy of SciencesPeer-reviewedDec 13, 2021

Genome instability drives epistatic adaptation in the human pathogen Leishmania

Giovanni Bussotti, Laura Piel, Pascale Pescher…·Gerald Frank Späth

The paper shows genome instability in Leishmania enables fitness gain through epistatic gene copy number variations and compensatory post-transcriptional mechanisms.

46 citationstop 3%

humanexperimental assay

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BioinformaticsNucleic Acids ResearchPeer-reviewedDec 3, 2021

GIP: An open-source computational pipeline for mapping genomic instability from protists to cancer cells

Gerald Frank Späth, Giovanni Bussotti

GIP is a computational pipeline for analyzing genome instability across species, identifying aneuploidy, copy number variations, and chromosomal rearrangements in microbial and cancer genomes.

13 citations

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