ImmunologybioRxivPreprint
IRF4 is a master regulator of multinucleated giant cell formation
Melanie Hofmann, Gerwin Heller, Markus Kieler…·Gernot Schabbauer
This study identifies IRF4 as a master regulator of multinucleated giant cell formation through integrated single-cell and bulk RNA sequencing, CRISPR/Cas9 editing, and in vivo fate mapping.