Author

Birgit Niederreiter

Medical University of ViennaORCID 0000-0002-6032-3499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1

Frequent Co-Authors

Gernot SchabbaueriD· 2 shared Gerwin HelleriD· 2 shared Leonhard X. HeinziD· 2 shared Melanie HofmanniD· 2 shared Ana KoroseciD· 1 shared Anahita Sedighi· 1 shared Anela TosevskaiD· 1 shared Axel DietschmanniD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Gernot SchabbauerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

IRF4 is a master regulator of multinucleated giant cell formation

Melanie Hofmann, Gerwin Heller, Markus Kieler, Laszlo Musiejovsky, Lukas Kremp, Martina Kerndl, Paul Ettel, Birgit Niederreiter, Lucia Quemada Garrido, Anahita Sedighi, Thomas Krausgruber, Leonhard X. Heinz, Axel Dietschmann, David Voehringer, Bart Everts, , Gernot Schabbauer

This study identifies IRF4 as a master regulator of multinucleated giant cell formation through integrated single-cell and bulk RNA sequencing, CRISPR/Cas9 editing, and in vivo fate mapping.

bioRxiv · Nov 3, 2025 · PreprintImmunology

Nicotinamide N-Methyltransferase drives fibroblast activation and skin fibrosis in systemic sclerosis

Anela Tosevska, Karolina von Dalwigk, Peter Heil, Felix Kartnig, Ana Korosec, Birgit Niederreiter, Juan Manuel Sacnun, Thomas Köcher, Daniel Aletaha, Hans Peter Kiener, Beate M. Lichtenberger, Leonhard X. Heinz, Thomas Karonitsch

This study identifies NNMT as a key driver of fibroblast activation and skin fibrosis in systemic sclerosis by modulating TGFβ signaling and ECM production.

bioRxiv · Oct 27, 2025 · PreprintImmunology

MiR-146a controls age related bone loss

Victoria Saferding, Melanie Hofmann, Julia S. Brunner, Birgit Niederreiter, Melanie Timmen, Nathaniel Magilnick, Silvia Hayer, Gerwin Heller, G.E. Steiner, Richard Stange, Mark Boldin, Gernot Schabbauer, Moritz Weigl, Matthias Hackl, Johannes Grillari, , Stephan Blüml

This study identifies miR-146a as a key regulator of age-related bone loss, showing its role in controlling bone homeostasis through Wnt signaling and its potential as a therapeutic target.

bioRxiv · Mar 20, 2020 · PreprintMolecular Biology