Author

Andrëw G. Brööks

The University of MelbourneORCID 0000-0002-4085-9683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1

Frequent Co-Authors

Adham Abuelola MohamediD· 1 shared Charlotte Hunkler· 1 shared Christina WallerathiD· 1 shared Gunther HartmanniD· 1 shared Jamie RossjohniD· 1 shared Julian P. VivianiD· 1 shared Martin J. MaiersiD· 1 shared Martin SchleeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Adham Abuelola MohamedORCID

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2 papers

Recent·Most cited

RIG-I Stimulation Enhances Effector Function and Proliferation of Primary Human CD8 T Cells

Adham Abuelola Mohamed, Christina Wallerath, Charlotte Hunkler, Gunther Hartmann, Sanda Stankovic, Andrëw G. Brööks, Martin Schlee

This study shows that RIG-I stimulation enhances CD8 T cell effector function and proliferation, both through IAV infection and 3p-dsRNA transfection.

International Journal of Molecular Sciences · Mar 27, 2026Peer-reviewedImmunology

Prediction of KIR3DL1/Human Leukocyte Antigen binding

Martin J. Maiers, Yoram Louzoun, Phillip Pymm, Julian P. Vivian, Jamie Rossjohn, Andrëw G. Brööks, Philippa M. Saunders

The paper builds a machine learning model to predict KIR3DL1 binding to HLA class I allotypes, showing that binding is influenced by multiple non-additive regions beyond the classical Bw4 motif.

Journal of Biological Chemistry · Jul 2, 2025Peer-reviewedImmunology