Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation.
James J. M. Cooper, Jessie J. Polanco, Darpan Saraswat, Jennifer J. Peirick, Anna Seidl, Yi Li, Dan Ma, Fraser J. Sim
This study shows that chronic demyelination in rabbit CNS is associated with reduced oligodendrocyte progenitor cell (OPC) repopulation, regardless of lesion size, and highlights species-specific differences in remyelination mechanisms.
Glia · Dec 20, 2022Peer-reviewedNeuroscience