Author

Boon Cher Goh

National University of SingaporeORCID 0000-0002-4107-102XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Melissa J. FullwoodiD· 2 shared Benjamin LebeauiD· 1 shared Chee Keong KwohiD· 1 shared Fanny DaoiD· 1 shared Hao LiniD· 1 shared Hao LviD· 1 shared Hideki MakinoshimaiD· 1 shared Joji NakayamaiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Melissa J. FullwoodORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

AI4Loop: an Artificial Intelligence Framework Reveals Increased 3D Chromatin Interactions and Therapeutic Vulnerabilities across 12,000 Cancer Samples

Fanny Dao, Benjamin Lebeau, Prachi Amuley, Wei Kit Tan, Xinya Li, Boon Cher Goh, Wee Joo Chng, Chee Keong Kwoh, Hao Lin, Hao Lv, Melissa J. Fullwood

AI4Loop uses deep learning to infer chromatin interactions from RNA-seq data, revealing increased interactions in tumors and identifying potential therapeutic compounds.

bioRxiv · Aug 18, 2026 · PreprintBioinformatics

A chemical screen based on an interruption of zebrafish gastrulation identifies the HTR2C inhibitor Pizotifen as a suppressor of EMT-mediated metastasis

Joji Nakayama, Lora Tan, Yan Li, Boon Cher Goh, Shu Wang, Hideki Makinoshima, Zhiyuan Gong

The paper identifies Pizotifen as an anti-metastasis drug by screening chemicals that disrupt zebrafish gastrulation and show it suppresses EMT-mediated metastasis through HTR2C inhibition.

eLife · Dec 17, 2021Peer-reviewedDevelopmental Biology

Biop-C: A Method for Chromatin Interactome Analysis of Solid Cancer Needle Biopsy Samples

Sambhavi Animesh, Ruchi Choudhary, Xin Yi Ng, Joshua K. Tay, Wan-Qin Chong, Boon Cher Goh, Melissa J. Fullwood

The paper introduces Biop-C, a modified Hi-C method for analyzing 3D genome organization in solid cancer needle biopsy samples, and identifies TADs, loops, and FIREs in nasopharyngeal cancer.

bioRxiv · Jan 11, 2021 · PreprintGenomics