Author

Sambhavi Animesh

National University of SingaporeORCID 0000-0003-0692-4434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:Hi-C· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Melissa J. FullwoodiD· 2 shared Andrew E. H. EliaiD· 1 shared Ben K. Wesley· 1 shared Ben S. WittneriD· 1 shared Boon Cher GohiD· 1 shared Cem TanrıöveriD· 1 shared Chee Keong KwohiD· 1 shared D. GulhaniD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioinformatics

Melissa J. FullwoodORCID

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3 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 6, 2025

The E3 ligase HECTD4 regulates COX-2 dependent tumor progression and metastasis

Joanna A. Vuille, Cem Tanrıöver, Ezgi Antmen…·Daniel A. Haber

The paper identifies HECTD4 as a tumor and metastasis suppressor that targets COX-2 for degradation, with COX-2 stabilization driving pro-tumorigenic effects in breast cancer.

5 citations

humanproteomics

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BioinformaticsGenome biologyPeer-reviewedAug 16, 2021

Chromatin Interaction Neural Network (ChINN): A machine learning-based method for predicting chromatin interactions from DNA sequences

Fan Cao, Yu Zhang, Yichao Cai…·Melissa J. Fullwood

ChINN predicts chromatin interactions from DNA sequences, showing good performance across samples and identifying sequence features associated with interactions in CLL patient data.

66 citationstop 4%

humanChIP-seq

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GenomicsbioRxivPreprintJan 11, 2021

Biop-C: A Method for Chromatin Interactome Analysis of Solid Cancer Needle Biopsy Samples

Sambhavi Animesh, Ruchi Choudhary, Xin Yi Ng…·Melissa J. Fullwood

The paper introduces Biop-C, a modified Hi-C method for analyzing 3D genome organization in solid cancer needle biopsy samples, and identifies TADs, loops, and FIREs in nasopharyngeal cancer.

DOI 10.1101/2021.01.11.426176

humanHi-C

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