Author

Robert A. Piscopio

University of California, Santa BarbaraORCID 0000-0002-4115-2874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Organism:human· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Maxwell Z. WilsoniD· 3 shared Siddharth S. DeyiD· 3 shared Alex ChialastriiD· 2 shared Chieh Ross WangiD· 1 shared Dasol HaniD· 1 shared Diego Acosta‐AlveariD· 1 shared Francesca ZappaiD· 1 shared Isobel Whitehead· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Maxwell Z. WilsonORCID

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3 papers

Recent·Most cited

Optogenetic Rescue Reveals Spatiotemporal Rules of Germ-Layer Patterning

Naomi J. Baxter, Robert A. Piscopio, Joseph Rufo, Dasol Han, Isobel Whitehead, Jasmine Dhillon, Siddharth S. Dey, Maxwell Z. Wilson

The paper uses optogenetics in human gastruloids to show that precise spatiotemporal WNT signaling controls germ-layer patterning.

bioRxiv · Dec 11, 2025 · PreprintDevelopmental Biology

Photolabile oligonucleotides combined with topologically imposed light gradients enable spatially resolved single-cell transcriptomics and epigenomics

Robert A. Piscopio, Alex Chialastri, Chieh Ross Wang, Mikolaj Godzik, Kellie A. Heom, Weiyue Wang, Maxwell Z. Wilson, Siddharth S. Dey

scSTAMP-seq enables spatially resolved single-cell transcriptomics and epigenomics by using photolabile oligonucleotides and light gradients to capture cell positions before sequencing.

bioRxiv · Oct 1, 2025 · PreprintGenomics

Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape

Taivan Batjargal, Francesca Zappa, Ryan J. Grant, Robert A. Piscopio, Alex Chialastri, Siddharth S. Dey, Diego Acosta‐Alvear, Maxwell Z. Wilson

This study uses optogenetic control of the ISR to show proportional encoding of stress inputs and reveals a stress memory landscape through an ODE model.

Cell Systems · Jul 1, 2023Peer-reviewedSystems Biology