ImmunologyNature ImmunologyPeer-reviewed
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Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis
Fumie Hayashi, Kristen Mittl, Ravi Dandekar…·Joseph J. Sabatino
Paired CSF and blood scRNA/TCR-seq in treatment-naive MS shows a small set of expanded, cytotoxic CSF-enriched CD8+ clonotypes, two of which recognize EBV epitopes.