Author

Kathleen Southern

Montreal Neurological Institute and HospitalORCID 0000-0002-4125-3608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

A.M. EdwardsiD· 1 shared Anita E. BandrowskiiD· 1 shared Carl LaflammeiD· 1 shared Claire M. BrowniD· 1 shared Donovan WorralliD· 1 shared Harvinder S VirkiD· 1 shared Ian McDowelliD· 1 shared Joël RyaniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

A.M. EdwardsORCID

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1 paper

Recent·Most cited

Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications

Riham Ayoubi, Joël Ryan, Michael Biddle, Walaa Alshafie, Maryam Fotouhi, Sara González Bolívar, Vera Ruíz Moleón, Peter Eckmann, Donovan Worrall, Ian McDowell, Kathleen Southern, Wolfgang Reintsch, Thomas M. Durcan, Claire M. Brown, Anita E. Bandrowski, , Carl Laflamme

Over half of 614 commercial antibodies for 65 human neuroscience proteins failed a knockout-controlled assay, yet most targets had a well-performing antibody; recombinants performed best.

eLife · Oct 5, 2023Peer-reviewedMolecular Biology✦ In-depth digest