Author

Joël Ryan

McGill UniversityORCID 0000-0002-7295-815XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:software / tool· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Claire M. BrowniD· 3 shared Alex Rigano· 2 shared Caterina Strambio‐De‐CastilliaiD· 2 shared Christopher B. MulhollandiD· 2 shared Heinrich LeonhardtiD· 2 shared Michelle S. ItanoiD· 2 shared Miha ModiciD· 2 shared Paula D.L.M. Montero LlopisiD· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBioinformatics

Claire M. BrownORCID

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Author profile →

5 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedOct 5, 2023

✦ In-depth digest

Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications

Riham Ayoubi, Joël Ryan, Michael Biddle…·Carl Laflamme

Over half of 614 commercial antibodies for 65 human neuroscience proteins failed a knockout-controlled assay, yet most targets had a well-performing antibody; recombinants performed best.

68 citationstop 1%

humanfluorescence / live-cell microscopy

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJun 23, 2021

MethodsJ2: A Software Tool to Improve Microscopy Methods Reporting

Joël Ryan, Thomas Pengo, Alex Rigano…·Claire M. Brown

MethodsJ2 is a software tool that collects metadata and generates text for the methods section of microscopy publications.

4 citations

imagingexperimental assay

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 31, 2021

Micro-Meta App: an interactive software tool to facilitate the collection of microscopy metadata based on community-driven specifications

Alex Rigano, Shannon R. Ehmsen, Serkan Utku Öztürk…·Caterina Strambio‐De‐Castillia

Micro-Meta App is an open-source tool that helps collect and organize microscopy metadata according to community standards, improving reproducibility and data sharing.

6 citations

imagingexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 15, 2021

Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation

Miha Modic, Igor Ruiz de los Mozos, Sebastian Steinhauser…·Jernej Ule

The paper identifies LIN28A as a key factor in mRNA decay during epiblast morphogenesis, linking cell identity changes to embryonic growth through nucleo-cytoplasmic translocation.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintApr 4, 2020

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive demethylation in mammals

Christopher B. Mulholland, Atsuya Nishiyama, Joël Ryan…·Heinrich Leonhardt

The paper identifies DPPA3 as a driver of genome-wide passive DNA demethylation in mammals, showing it can bypass TET protein requirements and function across species.

4 citations

mousezebrafish

𝕏 PostBluesky