Gerrald A. Lodewijk

The paper shows E2F1 induces cell-cycle reentry without changing chromatin accessibility by using pre-existing regulatory elements.

This paper shows that CRISPRa activation of two endogenous regulatory elements can self-organize ESCs into embryo-like structures with spatial and molecular features similar to pre-gastrulation mouse embryos.

DeepSea is a deep learning model for segmenting and tracking single cells in time-lapse microscopy images, showing cell size control in embryonic stem cells during G1 phase.

The paper identifies human-specific NOTCH2NL genes linked to neurodevelopmental disorders and shows they affect cortical neurogenesis through Notch signaling.