Author

Clara J. Han

University of California, Santa Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Abolfazl Zargari· 2 shared Benjamin R. TopacioiD· 2 shared Gerrald A. LodewijkiD· 2 shared S. Ali ShariatiiD· 2 shared Sayaka KozukiiD· 2 shared Seung‐Ho LeeiD· 2 shared Edward Wu· 1 shared Eric MalekosiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

Abolfazl Zargari

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2 papers

Recent·Most cited

E2F1 induces a G0-G1 reentry transcriptional program without changing chromatin accessibility

Gerrald A. Lodewijk, Benjamin R. Topacio, Seung‐Ho Lee, Sayaka Kozuki, Znala Williams, Clara J. Han, Abolfazl Zargari, Tilini U. Wijeratne, Neda Hajiakhoond Bidoki, Silvart Arabian, Edward Wu, Eric Malekos, Joscha Weiss, Gerd A. Müller, Vanessa D. Jönsson, , S. Ali Shariati

The paper shows E2F1 induces cell-cycle reentry without changing chromatin accessibility by using pre-existing regulatory elements.

bioRxiv · Sep 23, 2025 · PreprintCell Biology

Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing

Gerrald A. Lodewijk, Sayaka Kozuki, Clara J. Han, Benjamin R. Topacio, Abolfazl Zargari, Seung‐Ho Lee, Gavin T. Knight, Randolph Scott Ashton, Lei S. Qi, S. Ali Shariati

This paper shows that CRISPRa activation of two endogenous regulatory elements can self-organize ESCs into embryo-like structures with spatial and molecular features similar to pre-gastrulation mouse embryos.

bioRxiv · Mar 5, 2024 · PreprintDevelopmental Biology