Xiao Z. Shen

This study identifies Piezo1 as a mechanoreceptor in kidney medulla macrophages that enables them to clear sedimentary particles and prevent kidney stones.

This study evaluates the efficacy of intravesical delivery for kidney targeting in mice, showing improved therapeutic outcomes and reduced side effects compared to systemic delivery.

The paper identifies a subset of microglia in the paraventricular zone that clean cerebrospinal fluid by phagocytosing exogenous particles and prevents ventriculomegaly when removed.

This study identifies kidney cortex macrophages as a novel source of phosphate reabsorption, preventing calcium phosphate stone formation by upregulating SLC34A1 in response to mineral crystals.

The paper identifies PVN microglia as mediators of sympathetic excitation in hypertension through P2Y12 receptor signaling triggered by vascular ATP release.