From junk to deleterious: Natural subtelomeric repeat amplifications impact fitness and cellular phenotypes in yeast
Mathieu Hénault, Virginia Fogg, Lydia R. Heasley
The paper shows that subtelomeric repeat amplifications in yeast reduce fitness and alter cellular phenotypes, moving repetitive DNA from neutral to deleterious.
bioRxiv · Jul 3, 2026 · PreprintGenomics