Stian Knappskog

Interactions between neutrophils and macrophages harboring gram-negative bacteria promote obesity-associated breast cancer

The paper identifies a cellular network involving neutrophils and M2 macrophages in obese breast cancer patients that promotes tumor growth through bacterial LPS and S100A8.

Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development

The paper identifies prenatal BRCA1 epimutations as a cause of approximately 20% of triple-negative breast cancers and low-ER expression breast cancers.

epialleleR: an R/Bioconductor package for sensitive allele-specific methylation analysis in NGS data

The paper introduces epialleleR, an R/Bioconductor package for detecting low-level mosaic methylation events in NGS data, showing its performance on simulated and real datasets.

ramr: an R package for detection of rare aberrantly methylated regions

ramr identifies rare aberrantly methylated regions from methylation data, showing its utility in cancer and disease risk association.

The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer

The paper identifies two novel miRNAs, hsa-miR-nov3 and hsa-miR-nov7, overexpressed in breast cancer and correlates their expression with tumor subtypes and patient outcomes.